Cannabidiol (CBD) and cannabidiol (CBN) are two of the more than 100 cannabinoids found in cannabis plants. The endocannabinoid system consists of endocannabinoids that may bind to a variety of endocannabinoid receptors throughout the body.
Although this is true, it is only one of the reasons why cannabidiol (CBD) has become so popular. Since several states have legalized recreational marijuana, CBD goods have increased in popularity. Many people use CBD medicines to alleviate anxiety and chronic pain symptoms.
There have been few, if any, human studies on the possible advantages of CBN. However, there are a few tiny trials that suggest it may help with pain alleviation and induce sleep. Let’s take a look at CBD vs. CBN and their differences in terms of benefits and distinctions.
What are the benefits and uses of CBD?
CBD, unlike tetrahydrocannabinol (THC), is a non-psychoactive cannabinoid. CBD does not make you feel high like THC; it’s used to treat pain and anxiety. There are still many unanswered questions about CBD research, but preliminary studies have yielded promising findings and suggested that it has an excellent safety profile.
CBD is sold in a variety of forms, including:
- gummies
- oils and tinctures
- creams and lotions
- capsules and pills
- vapes
Here’s what the research says so far about CBD’s potential benefits:
Anxiety and depression management
CBD has shown promise as a potential therapy for anxiety and depression in the absence of traditional options. CBD’s effects are attributed to its interaction with 5-HT1A receptors, according to a reliable source.
In 2019, researchers gave 57 individuals who had to give a public speech either a placebo or 150, 300, or 600 mg of CBD before doing so. According to the study’s findings, people who received 300 mg of CBD experienced considerably less anxiety. In a 2019 research led by Dr. Scott Shannon, participants with an anxiousness or sleep issue were given 25-175 mg of CBD per day for one month. Increased anxiety symptoms were reported by 79.2 percent of persons at the one-month mark.
Neuroprotection and seizure reduction
According to an independent study published in 2020, cannabidiol (CBD) may be a viable therapy option for a variety of neurogenerative diseases.
Research is ongoing on CBDs potential to treat:
- Parkinson’s disease
- Alzheimer’s disease
- epilepsy
- multiple sclerosis
Epidiolex, a CBD-based pharmaceutical medication known as Epidiolex, has gained FDA approval as a treatment for Lennox-Gastaut and Dravet syndromes (two severe forms of epilepsy) and tuberous sclerosis complex seizures.
Sleep
Many users of CBD claim that it helps them sleep better. There is some scientific evidence suggesting that CBD may help people sleep better, but more research is needed to determine its full potential. In Dr. Scott Shannon’s 2019 study, 66.7 percent of participants who consumed between 25 and 175 mg of CBD daily reported improved sleep quality after one month.
Pain relief
It has been suggested that CBD activates the body’s endocannabinoid system, according to a 2018 studyTrusted Source. Seven transplant patients who had just completed treatment with 50 to 150 mg of CBD twice a day for 3 weeks had no improvement in overall pain, four experienced modest relief, and two completely relieved total pain.
Cancer treatment
CBD is a chemical compound derived from the hemp plant that has shown to help with a variety of problems caused by cancer therapy, including discomfort and nausea. Some early research suggest that CBD might have anti-cancer effects. In 2019, a review of studies published in Trusted Source highlighted in vitro and in vivo research demonstrating CBD’s effectiveness against pancreatic tumors. Pancreatic cancer was the focus of the study.
What are the benefits and uses of CBN?
CBD is a by-product of THC metabolism. It has a mild psychotropic effect and does not give the same high as THC. CBN isn’t studied as extensively as CBD. There’s currently little known about its potential advantages due to lack of research. CBN products are frequently marketed for use as sleep aids despite the fact that there’s still much to learn about them. The following are some examples of CBN’S prevalent applications and potential benefits:
Sleep
CBN is thought to aid in sleep. However, there’s just one trial on record that shows it has a sleep-inducing effect – it took place in 1975 and involved only five males. According to the study, those who ingested a blend of THC and CBN had greater sedative effects than those who took THC alone.
Pain relief
CBD and CBN were found to reduce myofascial pain in a 2019 rat research, according to the researchers. In addition, a combination of CBN and CBD was more effective than either singly at reducing TMJ pain and fibromyalgia discomfort. According to the researchers, CBN and CBD may help with TMJ pain.
Neuroprotective effects
CBN was able to delay the onset of amyotrophic lateral sclerosis in rats, according to a 2005 studyTrusted Source. It’s still unclear whether it has an effect on humans, but it’s possible that it does.
Anti-inflammatory effects
Rats that received CBN exhibited decreased inflammation, according to some research. However, human study is required to fully understand CBN’s capabilities.
What are the primary differences between CBD and CBN?
Despite their similar names, CBD and CBN are two distinct compounds. Cannabis plants contain the second most prevalent cannabinoid after THC. Breeders may try to enhance the amount of CBD in their strains by mating them. nBecause it is derived from THC decomposition, CBN is unavoidable. Heat can speed up the degradation of THC into CBN.
There hasn’t been a lot of study on the cannabinoids as a pair. However, there is considerably more CBD research taking place right now. As a result, CBD is often easier to come by. CBN isn’t FDA approved for the treatment of any diseases.
What are the potential side effects of CBD vs. CBN?
Cannabidiol (CBD) is a non-intoxicating cannabinoid that has a favorable safety and effectiveness profile. The most common adverse effects are as follows:
- diarrhea
- tiredness
- changes in weight and appetite
Cannabidiol (CBD) taken alone or in combination with other medications, such as ethanolamine citrate, might harm the liver. Certain medicines, for example:
- leflunomide
- lomitapide
- mipomersen
- pexidartinib
- teriflunomide
- valproate
However, CBN has no known bad effects, but this does not indicate that there aren’t any. It simply indicates that CBN hasn’t been studied enough to discover them.
Talk with a doctor if you’re interested in using CBD or CBN
It’s critical to talk with your doctor before starting CBD, CBN, or any other new supplements. A doctor can help you establish a good beginning dose and check whether the product has the ability to combine with any of your current medicines.
Although CBD or CBN may have potential as a supplement to your current treatment, you should not use them instead of tried-and-true therapies and processes.
Takeaway
CBN and CBD are two cannabinoids found in marijuana. Cannabinoids are still being studied, with only a few studies available on each.
CBD has thus far attracted more research. There is some evidence that it may assist with chronic pain, anxiety, and depression, among other things.
CBN is also disadvantageous, according to the Harvard Business Review. It’s tough to know if those advantages outweigh those of other sorts of complicated carbohydrates because there isn’t much research comparing CBN with other carbs. Meanwhile, as previously stated, there is no evidence suggesting that CBN has any benefits or drawbacks over other nutrients. CBN still requires a significant amount of human study before we can make any judgments about its potential advantages.