What is sativa, and what does the label tell you?
Scientists generally treat all cannabis as one species, Cannabis sativa. The sativa on a menu is something else: a vernacular label that breeders, sellers and users attach to a strain to suggest its look, aroma and effects. Two large studies have tested whether it tracks anything measurable.
In a 2021 study in Nature Plants, researchers genotyped 137 samples at more than 116,000 genetic markers and found sativa- and indica-labelled flower genetically indistinct across the genome. Samples sharing a name, such as OG Kush, were often as different from each other as samples with different names.
A 2022 study in PLOS ONE, covering 89,923 lab-tested flower samples from six US states, reached the same verdict on chemistry: a sample labelled indica was likely to have a terpene profile indistinguishable from samples labelled sativa or hybrid.
The label is not pure noise. In the Nature Plants data, sativa labels went with more bergamotene and farnesene, terpenes with tea-like and fruity aromas, while indica labels went with myrcene; the authors suggest growers assign labels mainly by aroma and purported effects. In the PLOS ONE data, one high-terpinolene group held about twice as many sativa-labelled products as expected.
