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Indica vs Sativa vs Hybrid: What the Labels Mean and What Matters More

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Indica vs Sativa vs Hybrid: What the Labels Really Mean

Indica, sativa and hybrid at a glance

How the 3 labels are usually used, and what research has found behind each:

  • Indica. Sold as the relaxing, sedating option. Botanists in the 1970s and 1980s described indica plants as short, conical and densely branched with short, broad leaflets, as Wikipedia's Cannabis indica entry summarizes. In lab studies, indica-labelled samples tend to contain more myrcene, an earthy-smelling terpene.
  • Sativa. Sold as the uplifting, energizing option. The same botanists described sativa plants as tall and loosely branched with long, narrow leaflets. Sativa-labelled samples lean toward farnesene and bergamotene, terpenes with fruity and tea-like aromas, and are over-represented among terpinolene-rich products.
  • Hybrid. A cross of both lines, often sold as indica-dominant, sativa-dominant or balanced. Dalhousie University researchers note that most cannabis grown and consumed today is a mashup of the 2 ancestral lineages, so most products are hybrids whatever the label says.

Where the words indica and sativa came from

Carl Linnaeus named Cannabis sativa in 1753, a name that referred to hemp, the plant grown for its seeds and fibre, according to the American Institute of the History of Pharmacy. In 1785 Jean-Baptiste Lamarck described a second species, Cannabis indica. His description, translated in a 1975 UN Bulletin on Narcotics paper, says the plants were collected in India and calls them smaller and more branched, with very narrow leaflets, the opposite of today's broad-leaf indica stereotype.

Today's plant-shape stereotypes came later, from 20th-century botanists such as Richard Evans Schultes (1974) and Loran C. Anderson (1980). A 2017 paper in The Botanical Review argues that 20th-century botanists helped spread a vernacular 'Sativa' and 'Indica' that does not match the original species, and that both groups are, botanically, subpopulations of a single subspecies. Botanists still debate whether cannabis is a single species or several.

Today the words mostly describe expected effects. As the AIHP exhibit puts it, sellers' use of sativa and indica describes 'the perceived effects of the marijuana strain, rather than the taxonomic difference.'

What genetic and chemical studies found

Several research teams have tested whether the labels match what is inside the plant:

  • 2015, PLOS ONE. A team including Dalhousie University researchers genotyped 81 marijuana and 43 hemp samples and found only a moderate match between genetics and reported indica or sativa ancestry. Jamaican Lambs Bread, reported as 100% sativa, was nearly identical to a reported 100% indica strain from Afghanistan, though the authors could not rule out a sample mix-up (Sawler et al.).
  • 2019, Journal of Cannabis Research. A genetic study of 30 strains bought from dispensaries in 3 US states found genetic groups that did not line up with indica, hybrid and sativa labels, and most strains had at least 1 sample that was a genetic outlier (Schwabe and McGlaughlin).
  • 2021, Nature Plants. A Dalhousie-led team re-analyzed 297 samples for 40 terpenes and cannabinoids and genotyped 137 of them at more than 116,000 genetic markers. Indica- and sativa-labelled samples were genetically indistinct across the genome, and overall genetic structure explained only 37% of how samples were labelled (Watts et al.).
  • 2022, PLOS ONE. An analysis of 89,923 lab-tested flower samples from 6 US states found indica, hybrid and sativa products 'highly intermingled' by terpene profile. Simply labelling each sample by its dominant terpene sorted them better than the industry labels did (Smith et al.).

Strain names, and what the labels do track

Strain names are not much better. The Nature Plants team found that samples sharing a name, such as OG Kush, were often as different genetically and chemically as samples with different names. As one of the researchers noted for Dalhousie News, a strain called AK-47 won the Sativa Cup at the 1999 Cannabis Cup and the Indica Cup 4 years later.

The labels are not pure noise, though. In the Nature Plants data, myrcene alone explained about 21% of the variation in how samples were labelled, with indica-labelled samples containing more of it. The researchers think growers have been assigning labels mainly by aroma and purported effects.

Do indica and sativa actually feel different?

Many people say they do. In a 2023 Arizona State University study that followed 101 regular users for 2 weeks, 78.3% preferred either sativa or indica, for reasons that matched industry claims (Okey et al.). After accounting for THC, expectations and other factors, strains classified as indica-dominant (using Leafly's categories) were linked to more low-arousal feelings, such as sluggishness. The authors call the work preliminary and say controlled lab studies are needed.

A 2020 analysis of Leafly reviews covering more than 800 strains also found that people describe indica- and sativa-tagged strains in clearly different terms, though the tags were assigned by Leafly users and the authors note that strain names can bias what reviewers report (de la Fuente et al.).

On the other side, the 89,923-sample study concluded there is currently no clear scientific evidence that the labels predict effects. Neurologist and cannabis researcher Ethan Russo has called the distinction as commonly used 'total nonsense', arguing that the differences people notice come mainly from terpenes such as myrcene (Piomelli and Russo, 2016). That terpene idea, often called the entourage effect, has itself been hard to confirm experimentally, the PLOS ONE authors note.

The fair reading: the label may carry a weak hint about aroma and feel, but it is not a reliable guide on its own.

What predicts the experience better

These factors have clearer support than the indica or sativa label:

  • How much THC you take. THC is responsible for the high and intoxication, according to Health Canada, which notes that harmful effects may be greater when THC is stronger. Small amounts can feel pleasant, while large amounts may bring unpleasant effects such as anxiety or paranoia. Look for clear THC and CBD numbers for the batch in front of you, ideally from a lab test, since the same product can vary in potency from batch to batch.
  • CBD, with a caveat. CBD does not produce the intoxicating effects THC does. Health Canada says there is some evidence that CBD may lower some of THC's effects on the mind when there is at least as much CBD as THC, but a 2023 randomized trial in Neuropsychopharmacology found that adding CBD at 1:1 to 3:1 ratios did not measurably change the effects of 10 mg of vaporized THC in 46 infrequent users.
  • Dose and format. Inhaled cannabis is felt within seconds to minutes and can take up to 30 minutes to reach its full effect. Edibles can take 30 minutes to 2 hours to be felt and up to 4 hours for the full effects, per Health Canada.
  • Terpenes. Terpenes give cannabis its smell, and the Arizona State study found early hints that a strain's dominant terpene may shape effects too. Our guide to cannabis terpenes explains the main ones.
  • You. Everyone's response to cannabis differs and can vary from one time to the next, according to Health Canada's consumer information.

Hybrids: what indica-dominant and sativa-dominant mean

A hybrid is a cross between indica-type and sativa-type parents. The 2 lines have been interbred so much that, in Russo's words, only a lab test 'tells a potential consumer or scientist what is really in the plant', and you cannot guess a plant's chemistry from its height, branching or leaf shape.

Labels such as indica-dominant, sativa-dominant, balanced or 75/25 come from breeders and sellers. In the Nature Plants study, samples were sorted on a 5-point scale from 100% sativa to 100% indica as reported by their sources, and those ratios lined up poorly with measured genetics. Read them as a hint about intended style, not a measurement.

Effects and risks to keep in mind

Whatever the label, THC can cause unwanted effects, especially at higher doses. Health Canada lists possible immediate effects including impaired memory and attention, anxiety, panic, paranoia, dizziness and an increased heart rate, and serious side effects such as extreme confusion, severe anxiety and hallucinations. If you take too much and feel unwell, call 1-844-POISON-X (1-800-463-5060 in Quebec) or 9-1-1, or go to the nearest hospital.

Health Canada advises choosing products with a low amount of THC and an equal or higher amount of CBD, starting low and going slow, and waiting to feel the effects before taking more. For medical questions, talk to a doctor or pharmacist.

How to use the labels when you shop

  • Use the label as a rough first filter at most, not a prediction.
  • Read the THC and CBD on the label for the batch in front of you. If you are new to cannabis or returning after a break, choose a lower-THC product.
  • Let aroma or the dominant terpene break ties; in the 89,923-sample study, dominant terpene grouped products better than the labels did.
  • With edibles, wait at least 2 hours before taking more, since full effects can take that long.
  • Note which products suit you, since even the same strain name can vary between growers.

Buying indica, sativa and hybrid flower

GasDank offers same-day delivery across Toronto and the GTA, usually within 1 to 2 hours, and mail order across Canada. Browse indica flower, sativa flower or hybrid flower; the menu carries lab-tested products. Customers must be 19 or older (21 in Quebec), with ID checked at the door.

About the author

Cannabis connoisseur with more than 25 years of experience with terpenes and cannabis flavours.

More from Steven De Guzman

Indica vs Sativa vs Hybrid: What the Labels Really Mean, FAQ

Q.Is indica or sativa better for sleep?

Indica is the label sellers use for evening, wind-down products, but research has not shown that the label reliably predicts how sleepy a product will make you. Cannabis is not a substitute for medical care, so talk to a doctor or pharmacist about ongoing sleep problems.

Q.Is sativa stronger than indica?

Neither label tells you strength. Potency depends on how much THC a product contains, and that varies from batch to batch, so compare the THC figure on the package instead.

Q.Which is better for beginners, indica or sativa?

Neither label makes a product beginner-friendly. What matters more is a low THC amount and a small first dose, then waiting to feel the effects before having more.

Q.What is ruderalis?

Ruderalis is a third name, given in 1925 by D. E. Janischevsky to wild hemp growing in parts of Russia. Some botanists count it as a separate species and others do not.

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