Cannabis for Inflammation: How Does It Work?

cannabis for inflammation how does it work - Cannabis for Inflammation: How Does It Work?

We’ve all felt the unpleasant ache of inflammation before. Whether it’s a stomach upset, a skin outbreak, or a twisted ankle, we’d all rather avoid inflammation as a symptom.

It turned out that we had very little control. Sure, inflammation is unavoidable in certain scenarios such as a sprained ankle or a broken bone (basically anything beyond your control). But the degree of the symptom’s intensity can be reduced, and the pain it causes may be eliminated to a significant extent.

Most of us may reduce our risk of chronic diseases by eating a nutritious diet that is high in anti-inflammatory substances and antioxidants. Nuts, leafy greens, and turmeric are some of the most popular choices. However, this isn’t a post about healthy dieting for sure.

Cannabis can aid in the prevention and management of inflammation. Cannabis may be utilized to reduce and control inflammation, as this is a topic about how it might be utilized to do so.

What Causes Inflammation?

Cannabis for Inflammation: How Does It Work?

Inflammation is a bodily function that fight against any sort of harm. Toxins, infections, and injuries can all cause an immune response, which results in inflammation.

For millenia, cannabis has been utilized to treat inflammation. Cannabinoids are similar to the endocannabinoids produced by our bodies’ endocannabinoid system.

How Is Marijuana an Effective Treatment for Inflammation?

CBD and THC work together to lower inflammation caused by a variety of conditions. Beta-caryophyllene, another component found in cannabis, activates the CB2 receptor.Researchers studied mice with swollen paws in a 2008 study. (Oral beta-caryophyllene doses reduced inflammation by 70% in mice that lacked CB2 receptors. Mice lacking CB2 receptors didn’t notice any benefits, either.) Endocannabinoids are produced within cells’ exterior surfaces and contain the CB1 and CB2 receptors, while the CB1 and CB2 receptors are located on the cell’s surface.

CBD and THC are two types of cannabinoids that both have anti-inflammatory properties. They not only treat and prevent inflammation, but they also reduce the production and release of pro-inflammatory cytokines. They also block STAT1 transcription factor activation induced by LPS, which is involved in inflammatory processes. CBD is most effective at reducing inflammation, therefore CBD-rich marijuana strains might be beneficial for those who suffer from severe inflammation.

What Symptoms of Inflammation Can Medical Marijuana Treat?

Cannabidiol helps your body maintain its natural cannabinoids, which help you fight illness and heal yourself.

Endocannabinoids help to control:

  • Muscle tone
  • Pain
  • Appetite
  • Mood state
  • Inflammation

There are over 100 different cannabinoids in marijuana, allowing it to modulate both descending and ascending pain pathways, as well as anti-inflammatory and neuroprotective processes.

How to Get Medical Marijuana for Inflammation

Not all states enable individuals to use cannabis for inflammation. To find out whether you qualify, chat with a qualified medical marijuana doctor in your state. A doctor can answer your queries and assist you in obtaining the therapy you require.

Best Methods of Marijuana Treatment to Use to Treat Inflammation

Cannabis is now more popular than ever before. It’s a viable alternative to prescription medicine that has addictive qualities and negative side effects. In many circumstances, medical cannabis for inflammation can help patients live a better quality of life than conventional medication.

Cannabis can be used in a variety of ways, both topically and internally, to treat inflammation. The following are some examples:


Vaporizers are becoming increasingly popular among patients who wish to use the inhalation method to acquire their prescription.


Medical marijuana is absorbed differently via the mouth than it is by inhalation. Dosing titration with the oral route is somewhat more challenging, and effect onset is delayed. It’s also a cost-effective and easy-to-use inflammation therapy delivery method.

  1. Transdermal

Cannabinoids, such as CBD and THC, are fat and alcohol soluble. When cannabinoids are incorporated into a cream or lotion, they seep through your skin and into your circulation.

  1. Topical

Lotions, oils, creams, and patches are all types of topical applications. Topical treatments target specific regions of pain. They’re long-lasting, non-psychoactive, non-invasive, and simple to use.

  1. Suppositories

Suppositories may be a good option for you. While it is not the most popular method of delivery, if you’re searching for therapy “on the road,” it might be a useful route. Before using, refrigerate the medication. This technique is quick, long-lasting, and effective.

  1. Sublingual

Sublinguals are available in tinctures and essential oils. They’re quick and simple to use. They’re popular with children because they’re handy and the most common way to take medicines.

When it comes to beginning your marijuana therapy for inflammation, there are a few things to think about when choosing a medical marijuana facility:

  • Selection of cannabis available
  • Quality of marijuana
  • Attention to customers
  • Price of weed
  • Safety and health regulations
  • Delivery and location services
  • Transparency

Best Strains of Marijuana for Inflammation

Critical Kush

The insanely popular Barney’s Farm created the potent cross between the insanely popular Critical Mass X OG Kush strains, and this heavy indica dominance (90% indica/10% sativa) strain is called a heavily indica dominant hybrid (90% indica/10% sativa). This dank bud has a moderately high THC concentration ranging from 14-20 percent on average, as well as a powerful mix of indica and sativa effects. Users describe the Critical Kush high as a slowly developing hazy calm body high with a touch of euphoria.

With maximum pain alleviation as well as a sense of contentment and elevation, you’ll feel totally at ease. As the high wears off, you’ll enter into a profound state of meditation, with a gradually building sensation of sedation that will eventually lead to a deep and pain-free sleep. Critical Kush is said to be an ideal strain for treating patients suffering from problems including stress, chronic pain due to injury or illness, minor to moderate cases of depression, and sleep disorders including insomnia and night terrors because to its potent effects. The flavor of Earthy Kush is earthy pine with a sweetly spicy aftertaste on exhale, and it has an aroma of earthy spicy pine. These nuggets have dense fluffy popcorn-shaped light minty green nugs with dark orano the endocannabinoids produced in our endocannge hairs, rich purple undertones, and a surface of fine translucent trichomes.

Cannabis for Inflammation: How Does It Work?


This cannabis strain has already been covered. CBD is abundant in Cannatonic. Cannatonic is a 1:1 CBD and THC cannabis strain, to be more precise. This distinction makes Cannatonic stand out. Cannatonic is a Spanish-bred cannabis strain that was created by crossing Reina Madre with NYC Diesel. Because of its CBD content, this marijuana strain is ideal for novices since it may help reduce paranoia and psychosis caused by THC.


This is another high-CBD strain. Harlequin is a great starting point for cannabis users. This Sativa-rich strain has a 5:2 CBD to THC ratio. Harlequin has a higher CBD content than Cannatonic, although it still has “fairly good” amounts of THC. Because of its high CBD concentration, Harlequin is also an excellent strain to start with for newcomers. Both CBD and THC are cannabinoids that reduce pain and inflammation. Joint discomfort and muscular soreness can be reduced using CBD hemp oil.

Harlequin is a great cannabis strain for arthritis relief. It’s also unlikely you’ll get THC-induced paranoia because to its high CBD content.


Cannabis plants with high CBD levels can help decrease inflammation. Another CBD-rich cannabis strain is AC/DC. This strain is highly regarded for medical usage, especially as a pain reliever. Many marijuana users swear by this strain’s abilities to combat nerve discomfort.

Tangie Sunrise

The Tangie Sunrise strain is a happy and uplifting experience for users. It has a high THC content (16 percent of THC), making it ideal for soothing inflammation, stress, tiredness, and sadness. Tangie Sunrise is a cross between Jack Herer and Orange Crush.

Girl Scout Cookies

The absolute best way to understand how a strain of marijuana effects you is to try it for yourself. -> GSC, sometimes known as GSC, is one of the most potent strains with a THC content of 19 percent (GSC). This Kush variety is also a member of the Kush family. Girl Scout Cookies combines OG Kush and Durban Poison to make a medicinal hybrid. Chronic inflammation can be effectively treated using this strain.

The Gift

The Gift is a hemp strain that has been derived from the male plant of the Indica-dominant hybrid cultivar G13. The name derives from its association with the female parent, which is also known as RG8 (short for Ristretto Guadi OG). This strain contains a high level of CBD and very little THC, making it ideal for people seeking relaxing and anti-inflammatory effects without experiencing euphoria or mind altering effects. The Gift is especially great for people who want anti-inflammatory benefits without risking paranoia or insanity. In addition, this strain can be used to treat arthritis and sleeplessness.

The Anti-Inflammatory Benefits of Cannabis

The cannabis plant is comprised of a variety of chemicals known as cannabinoids, with 113 identified so far and potentially growing in number as researchers and botanists conduct research due to the growing interest surrounding the legal marijuana industry.

Cannabinoids, like other functional foods, have been found to dampen the inflammatory response and alleviate the symptoms it produces. Pain, fatigue, and a sense of discomfort are some of the symptoms.

Cannabinoids’ ability to reduce inflammation has made cannabis a subject of study in relation to autoimmune diseases such as multiple sclerosis, rheumatoid arthritis, colitis, and hepatitis, where the inhibition of inflammation may help the patient.

Cannabinoids “may also be beneficial in certain types of cancer that are caused by chronic inflammation,” according to Nagarkatti (2010). They have an immediate anti-inflammatory effect on tumor development.

What To Look For In Cannabis For Inflammation

The Cannabis sativa plant contains a lot of cannabidiol (CBD), which has anti-inflammatory qualities. CBD’s legality in all 50 states across the United States, as well as its non-psychoactive properties, are largely to thank for this.

Cannabidiol (CBD) has long been used to cure inflammation and localized physical agony. Cannabis plants, such as hemp and marijuana, contain a chemical called CBD (cannabidiol), which is similar to THC (the psychotropic component of cannabis) in terms of effects. Hemp is a non-psychoactive Cannabis sativa strain with more CBD than THC.

CBD, as a cannabinoid, has been shown to provide a variety of positive effects. CBD’s anti-inflammatory qualities are among them. As a result, the majority of the strains on our list have an increased concentration of CBD.

Side Effects of Marijuana for Inflammation

Marijuana, when compared to other inflammation-reduction techniques with known anti-inflammatory medication side effects, is a safe and natural therapy with little risk. While marijuana has the potential to have a variety of effects on the body, most side effects are minor and go away after you stop using it.

Some of the common side effects of marijuana include:

  • A high sensation: THC is the chemical in cannabis that causes a “high” feeling. When people smoke marijuana, they experience a sensation known as a “high.” Many individuals like this sense of euphoria, but it’s essential to be aware and prepared for the fact that this high might impair their abilities to drive or work.
  • Drowsiness: When you take cannabis to cure inflammation or other ailments, you might feel drowsy. This sensation may cause problems with numerous daytime activities. It can, however, be useful when attempting to fall asleep at night. For when you need to stay awake, a sativa-dominant strain is a good option.
  • Increased appetite: Patients who use medical cannabis have been known to report an increase in appetite. Depending on the person, this can be a beneficial or bad side effect. If the patient has a poor appetite or needs to put weight on for medical reasons, it is often considered a favorable consequence.

Inflammation can be quite uncomfortable and harmful. Many patients believe that the many potential side effects of medical marijuana are worthwhile in order to cure their inflammation. When compared to traditional anti-inflammatory medications and other types of therapy, cannabis is both affordable and natural.

Final Thoughts

The need for medical research on cannabis is one of the most pressing issues facing the marijuana business. Because of its illegal status across the world, much study has been restricted, but that’s starting to change in the United States. This should go a long way in helping us learn about which cannabis strains are best for inflammation in the future.

What we do know is that cannabis’ active components might help to decrease inflammation. Still, despite the promising early studies, we must learn more before drawing any conclusions.

Before using cannabis to treat inflammation or any other medical condition, we recommend consulting a physician. Medical marijuana laws differ greatly by state; therefore, double-check your knowledge and understanding of the rules in your area before proceeding.

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