The CBD sector is clearly blossoming. According to a research by Grand View Research, the worldwide market may be worth more than $23 billion by 2025. It’s already a multi-billion-dollar industry. Not terrible for such a “niche” industry just a few years ago.
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One of the most problematic aspects of the sector is the presence of false information. With so many people using CBD oils, it’s critical to understand the facts. However, we still see numerous websites make mistakes with their information.
CBD, for example, isn’t “non-psychoactive” because it isn’t “non-intoxicating,” which implies it doesn’t produce the same high as marijuana. CBD is also not immediately legal in all 50 states due to the fact that it has not yet been federally recognized.
Unfortunately, the general public is still in the dark about many aspects of cannabidiol. We hope to set the record straight in this article.
CBD Potentially Counteracts the Intoxicating Effects of THC
Cannabinoids are compounds found in the cannabis plant that have a variety of effects, including therapeutic and recreational. CBD and THC are the most well-known cannabinoids in the cannabis plant. Both are psychoactive since they impact nerve system functioning. This induces mood changes, behavior modifications, cognitive functions, perceptions, or awareness changes.
THC has a strong psychological effect, and the high it produces is intoxicating. CBD does not have this influence. These days, cannabidiol producers work hard to ensure that products have no more than 0.3 percent THC.
CBD also has anti-anxiety and anti-psychotic effects, which are thought to be caused by THC. Most THC-induced symptoms are due to the activation of CB1 and CB2 cannabinoid receptors. CBD, on the other hand, has a much lower affinity for these cannabinoid receptors. It is a relatively weak antagonist of CB1 receptors and a minor inverse CB2 agonist instead.
In 2013, a study published in Frontiers in Psychiatry investigated whether CBD neutralized THC’s intoxicating effects. CBD was found to be neuroprotective, which means it may have aided in the mitigation of THC’s harmful effects.
In 2012, a research published in the Journal of Psychopharmacology investigated the pot combination of THC and CBD. It revealed that CBD might protect against memory impairment and paranoia caused by THC.
A variety of people use a combination of CBD and THC. There are many renowned cannabis strains that have a 1:1 THC to CBD ratio. The following are examples:
- Sweet and Sour Widow
If you pick a 1:2 THC to CBD ratio, you will have a mild high while remaining unlikely to feel intoxicated.
The CBD for Pets Market Is Huge!
According to a study by Nielsen and Headset, the CBD pet product industry presents significant potential for entrepreneurs. It was discovered that nearly 74% of people who use CBD have pets. Furthermore, around a twentieth of American dog owners utilize hemp-derived CBD treatments. The product is used by half of these individuals to relieve pain or anxiety in their canine friend.
Animals, including dogs, cats, and horses, all have an endocannabinoid system similar to humans. As a result, CBD might be effective in the same way that it is on people.
At the moment, there is little research on CBD for pets. According to a 2017 analysis by the World Health Organization (WHO), CBD was both safe and well-tolerated in animals.
In 2018, a study published in Frontiers in Veterinary Science revealed that CBD helped improve activity and comfort in dogs with osteoarthritis. A subsequent research, published in the Journal of the American Veterinary Association in 2019, was also fascinating. CBD was found to potentially aid in the reduction of epilepsy seizures in dogs.
Both studies were well-designed and peer-reviewed. They were, however, preliminary because they included small groups of people. When CBD was fed to the dogs in both trials, their liver enzyme alkaline phosphatase (ALP) levels increased.
CBD Can Interact with Certain Pharmaceutical Drugs
Both of the aforementioned canine studies were authored by Stephanie McGrath. She advised pet owners not to give CBD to dogs with liver issues. This is due to the fact that CBD is metabolized by the liver. It can also cause problems in people, particularly those who are taking pharmaceutical medications.
Your body breaks down (metabolizes) things when you take a substance. The cytochrome P450 (CYP450) family of enzymes transforms foreign chemicals so they can be eliminated from the body. Certain compounds, however, notably medicines, slow or boost CYP450 activity. Drug metabolism can be slowed or accelerated by this mechanism.
The CYP450 pathway is used to break down various cannabinoids, including CBD. The CYP3A4 enzyme carries out this function. It also metabolizes approximately 60% of all prescription medicines. If you use CBD and a pharmaceutical remedy, you will alter the way that drug works.
CBD causes this by inhibiting CYP3A4, therefore it doesn’t metabolize the drugs in your body as efficiently. Your body may break down a medicine too slowly, resulting in too much medication in your system. Alternatively, it may metabolize the drug too quickly and reduce its efficacy.
Avoid CBD if you take medication that contains the ‘grapefruit’ caution. FURA-NCO is an ingredient found in grapefruit that inhibits CYP3A4. As a result, grapefruit has a similar impact on CYP3A4 as does CBD. Here are some of the most common medications with a grapefruit warning:
- Blood thinners
- Anticancer medications
- GI medications
- Erectile dysfunction medications
- Cholesterol medications
If you use one of the above, speak to your doctor before using CBD.
CBD Is Technically Illegal in Some States That Allow Marijuana!
CBD is not intoxicating, but it is technically illegal in a few jurisdictions. This is even the case in states where recreational marijuana is legal! In California, for example, you can lawfully consume cannabis if you are an adult aged 21 or older. However, the legality of CBD in California is unclear.
The Food, Drug, and Cosmetic Act of the United States is similar to California’s Sherman Food, Drug, and Cosmetic Law. The Sherman Law does not prohibit the sale of “adulterated” food.
The California Department of Public Health (CDPH) has not officially declared that hemp CBD is “adulterated.” However, it appears to be relying on the provision as a pretext for enforcement.
The Los Angeles Department of Public Health HAS claimed that hemp CBD is an adulterant. There isn’t a state law prohibiting the sale, processing, or consumption of hemp CBD outside of the licensed cannabis chain. Certain authorities, in theory, may use the Sherman Law or federal rules to prohibit certain CBD products.
It’s incredible that this legal loophole exists, and it’s the same in other states. Of course, companies wanting to sell CBD food and beverages in California should face no difficulties.
Only One CBD Product Is Federally Legal
The only CBD-based drug approved by the FDA is Epidiolex. To manage epileptic seizures, it may be obtained via a doctor’s prescription. Many websites claim that CBD is legal in all 50 states. Both claims are untrue, according to several sources.
The 2014 Farm Bill legalized the growth of industrial hemp with a THC concentration of no more than 0.3 percent. It did not explicitly legalize CBD or any other cannabinoid, although it allowed for such plants to be grown under certain conditions. The United States Department of Agriculture (USDA) must approve each state’s hemp growing plan. Almost every state has complied with this requirement.
The Farm Bill does not contain any provisions that would allow the sale, possession, or usage of CBD or any other cannabinoid. It’s an odd predicament because most hemp cultivated in the United States is for the CBD market!
Because it is not legally permitted, each state has the option to create rules. The CBD business is largely unregulated in most states. However, a handful of states make it difficult for businesses and consumers. We’ve heard of several CBD-related arrests!
In most cases, people looking for CBD in the United States have little trouble finding it.
Final Thoughts on Insane CBD Facts
Hopefully, this post has clarified things for you and shed light on some misconceptions. CBD isn’t yet legal in all 50 states, and it’s not yet internationally accepted. It isn’t either well regulated at present. As a result, you should focus on well-known brands that provide third-party lab reports for their goods.
CBD’s research is continuing, but early findings are quite encouraging. It is already a billion-dollar market, and it will undoubtedly expand at an exponential rate in the next few years.